HIV Viral Dynamic under Treatment with Intracellular Delay and Virus Decay as Interactive Parameters
DOI:
https://doi.org/10.5540/tcam.2021.022.02.00291Keywords:
Joint possibility distribution, interactive fuzzy numbers, HIV model, Viral dynamics,Abstract
Treatment with antiviral drugs for human immunodeficiency virus type 1 (HIV-1) infection causes a rapid reduction in plasma viral load. Viral decline occurs in several stages and provides information on important kinetic constants of virus replication in vivo and pharmacodynamic properties. We present a mathematical model that not only considers the intracellular phase of the viral life cycle, defined as the time between the infection of a cell and the production of new viral particles, but we also consider that this parameter together with the virus decay are interactive fuzzy numbers.References
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